{"id":11264,"date":"2025-03-10T11:38:20","date_gmt":"2025-03-10T10:38:20","guid":{"rendered":"https:\/\/skinboutique.pt\/?p=11264"},"modified":"2025-10-03T14:04:40","modified_gmt":"2025-10-03T13:04:40","slug":"pdrn-innovative-treatment-for-skin-rejuvenation","status":"publish","type":"post","link":"https:\/\/skinboutique.pt\/en\/treatments\/pdrn-innovative-treatment-for-skin-rejuvenation\/","title":{"rendered":"PDRN: Innovative treatment for skin rejuvenation"},"content":{"rendered":"<p><strong>Polydeoxyribonucleotide (PDRN)<\/strong> is a substance derived from <strong>salmon DNA<\/strong> with properties that help regenerate, rejuvenate and heal the skin.<\/p>\n<p>In this article, <strong>Dr. Mafalda Cleto<\/strong> (OM 52818), a <strong>general practitioner at Skin Boutique<\/strong>, gives us a lot of information about this promising agent. Find out what the benefits are, how the procedure works and the care required after application. <\/p>\n<p>&nbsp;<\/p>\n<h2><strong>Polydeoxyribonucleotide: The secret to younger-looking skin<\/strong><\/h2>\n<p><a href=\"https:\/\/skinboutique.pt\/en\/skin\/envelhecimento-pele-sinais\/\" target=\"_blank\" rel=\"noopener\">Skin ageing<\/a> is a natural and inevitable process that manifests itself with the appearance of <strong>wrinkles, sagging and dehydration<\/strong>. There are already minimally invasive techniques, such as <g id=\"gid_2\">chemical peels<\/g>, <g id=\"gid_3\">CO2 laser<\/g> and <a href=\"https:\/\/skinboutique.pt\/en\/treatments\/peeling-quimico\/\">botulinum toxin<\/a><g id=\"gid_5\">(Botox\u00ae<\/g>), which mitigate this process with satisfactory results. However, more recently, <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2096691122000723\" target=\"_blank\" rel=\"noopener\">clinical studies<\/a> indicate that products containing <strong>polynucleotides<\/strong> &#8211; such as Polidesoxyribonucleotide &#8211; have the ability to fill the &#8220;contracted&#8221; spaces in the skin and promote tissue regeneration.  <\/p>\n<p>PDRN thus proves to be an innovative treatment that promotes <strong>tissue repair<\/strong> and cell growth, resulting in a gradual, natural and prolonged improvement in the skin&#8217;s appearance.<\/p>\n<p>&nbsp;<\/p>\n<p>&#8220;PDRN <em>is a regenerative substance taken from the DNA of salmon cells. It is a safe product that aims to stimulate cell growth and has regenerative properties. What does this mean? It will help improve skin quality.<\/em>&#8221; &#8211; Dr. Mafalda Cleto (OM 52818) <\/p>\n<blockquote class=\"instagram-media\" style=\"background: #FFF; border: 0; border-radius: 3px; box-shadow: 0 0 1px 0 rgba(0,0,0,0.5),0 1px 10px 0 rgba(0,0,0,0.15); margin: 1px; max-width: 658px; min-width: 326px; padding: 0; width: calc(100% - 2px);\" data-instgrm-permalink=\"https:\/\/www.instagram.com\/reel\/C8Fa8v5MNQw\/?utm_source=ig_embed&amp;utm_campaign=loading\" data-instgrm-version=\"14\">\n<div style=\"padding: 16px;\">\n<p>&nbsp;<\/p>\n<div style=\"display: flex; flex-direction: row; align-items: center;\">\n<div style=\"background-color: #f4f4f4; border-radius: 50%; flex-grow: 0; height: 40px; margin-right: 14px; width: 40px;\"><\/div>\n<div style=\"display: flex; flex-direction: column; flex-grow: 1; justify-content: center;\">\n<div style=\"background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 100px;\"><\/div>\n<div style=\"background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; width: 60px;\"><\/div>\n<\/div>\n<\/div>\n<div style=\"padding: 19% 0;\"><\/div>\n<div style=\"display: block; height: 50px; margin: 0 auto 12px; width: 50px;\"><\/div>\n<div style=\"padding-top: 8px;\">\n<div style=\"color: #3897f0; font-family: Arial,sans-serif; font-size: 14px; font-style: normal; font-weight: 550; line-height: 18px;\">View this post on Instagram<\/div>\n<\/div>\n<div style=\"padding: 12.5% 0;\"><\/div>\n<div style=\"display: flex; flex-direction: row; margin-bottom: 14px; align-items: center;\">\n<div>\n<div style=\"background-color: #f4f4f4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(0px) translateY(7px);\"><\/div>\n<div style=\"background-color: #f4f4f4; height: 12.5px; transform: rotate(-45deg) translateX(3px) translateY(1px); width: 12.5px; flex-grow: 0; margin-right: 14px; margin-left: 2px;\"><\/div>\n<div style=\"background-color: #f4f4f4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(9px) translateY(-18px);\"><\/div>\n<\/div>\n<div style=\"margin-left: 8px;\">\n<div style=\"background-color: #f4f4f4; border-radius: 50%; flex-grow: 0; height: 20px; width: 20px;\"><\/div>\n<div style=\"width: 0; height: 0; border-top: 2px solid transparent; border-left: 6px solid #f4f4f4; border-bottom: 2px solid transparent; transform: translateX(16px) translateY(-4px) rotate(30deg);\"><\/div>\n<\/div>\n<div style=\"margin-left: auto;\">\n<div style=\"width: 0px; border-top: 8px solid #F4F4F4; border-right: 8px solid transparent; transform: translateY(16px);\"><\/div>\n<div style=\"background-color: #f4f4f4; flex-grow: 0; height: 12px; width: 16px; transform: translateY(-4px);\"><\/div>\n<div style=\"width: 0; height: 0; border-top: 8px solid #F4F4F4; border-left: 8px solid transparent; transform: translateY(-4px) translateX(8px);\"><\/div>\n<\/div>\n<\/div>\n<div style=\"display: flex; flex-direction: column; flex-grow: 1; justify-content: center; margin-bottom: 24px;\">\n<div style=\"background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 224px;\"><\/div>\n<div style=\"background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; width: 144px;\"><\/div>\n<\/div>\n<p>&nbsp;<\/p>\n<p style=\"color: #c9c8cd; font-family: Arial,sans-serif; font-size: 14px; line-height: 17px; margin-bottom: 0; margin-top: 8px; overflow: hidden; padding: 8px 0 7px; text-align: center; text-overflow: ellipsis; white-space: nowrap;\"><a style=\"color: #c9c8cd; font-family: Arial,sans-serif; font-size: 14px; font-style: normal; font-weight: normal; line-height: 17px; text-decoration: none;\" href=\"https:\/\/www.instagram.com\/reel\/C8Fa8v5MNQw\/?utm_source=ig_embed&amp;utm_campaign=loading\" target=\"_blank\" rel=\"noopener\">A post shared by Skin Boutique by LMR (@skinboutique.co.uk)<\/a><\/p>\n<\/div>\n<\/blockquote>\n<p><script async=\"\" onerror=\"var a=document.createElement('script');a.src='https:\/\/iframely.net\/files\/instagram_embed.js';document.body.appendChild(a);\" src=\"https:\/\/www.instagram.com\/embed.js\"><\/script><\/p>\n<h2><strong>4 Benefits of PDRN for skin health<\/strong><\/h2>\n<p>Polydeoxyribonucleotide is a <strong>collagen bio-remodeling compound<\/strong> known for its regenerative and <g id=\"gid_1\">anti-ageing<\/g> properties that has various <strong>advantages<\/strong>:   <\/p>\n<p>&nbsp;<\/p>\n<ol>\n<li><strong>Anti-inflammatory properties: <\/strong>Reduces inflammation and promotes a better balance in the epidermis by inhibiting inflammatory cytokines.<\/li>\n<li><strong>Accelerates healing: <\/strong>Promotes tissue repair, improves <strong>wound healing <\/strong>and reduces the appearance of <strong>imperfections and scars<\/strong>.<\/li>\n<li><strong>Improves skin texture: <\/strong>Stimulates collagen production, providing greater firmness, smoothness and a more youthful appearance.<\/li>\n<li><strong>Natural results: <\/strong>Unlike some more invasive procedures, PDRN improves the skin gradually and naturally.<\/li>\n<\/ol>\n<p>&nbsp;<\/p>\n<h2><strong>How does PDRN treatment work?<\/strong><\/h2>\n<p>PDRN is injected into strategic points on the skin to maximize the absorption and effectiveness of the substance.<\/p>\n<p>Although it is a <strong>minimally invasive and painless process<\/strong>, our <a href=\"https:\/\/skinboutique.pt\/en\/treatments\/skin-boutique-porto-lisboa-equipa\/\" target=\"_blank\" rel=\"noopener\">team of medical specialists<\/a> apply a topical anaesthetic before the treatment to make it more comfortable for the patient.<\/p>\n<ul>\n<li><strong>Recommended sessions:<\/strong> 3 to 5, 15 to 30 days apart.<\/li>\n<li><strong>Results:<\/strong> Visible after just a few sessions and can last up to a year.<\/li>\n<\/ul>\n<p><strong> <\/strong><\/p>\n<h2><strong>Which areas of the body can be treated with PDRN?<\/strong><\/h2>\n<p>PDRN is used on different parts of the body, the most common being:<\/p>\n<ul>\n<li><strong>Face<\/strong>: Improves skin tone and texture, takes care of <strong>signs of ageing<\/strong> and diminishes fine lines;<\/li>\n<li><strong>Neck<\/strong>: Rejuvenates sagging skin;<\/li>\n<li><strong>Hands<\/strong>: Fades the signs of ageing and improves skin texture and firmness;<\/li>\n<li><strong>Body<\/strong>: Promotes healing and regenerates areas affected by <strong>stretch marks<\/strong> or scars.<\/li>\n<\/ul>\n<p>Read more about: <a href=\"https:\/\/skinboutique.pt\/en\/sagging\/combater-flacidez\/\" target=\"_blank\" rel=\"noopener\">How to combat sagging facial skin<\/a><\/p>\n<p>&nbsp;<\/p>\n<h2><strong>Who can have this treatment?<\/strong><\/h2>\n<p>PDRN is a well-tolerated procedure and, as a general rule, can be applied to anyone looking to improve skin health, reduce the signs of ageing or <strong>regenerate tissue<\/strong>. Depending on the <strong>diagnosis<\/strong> and condition of each skin, it can be combined with other <a href=\"https:\/\/skinboutique.pt\/en\/treatments\/\" target=\"_blank\" rel=\"noopener\">medical-aesthetic treatments<\/a> to enhance the results. <\/p>\n<p>Although it is a safe treatment, there are particular cases that require some attention:<\/p>\n<ul>\n<li>Pregnancy;<\/li>\n<li>Breastfeeding;<\/li>\n<li>Skin infections;<\/li>\n<li>Autoimmune disorders;<\/li>\n<li>Allergies to the components used.<\/li>\n<\/ul>\n<p><strong> <\/strong><\/p>\n<p><strong>What care should be taken after the procedure?<\/strong><\/p>\n<p>&nbsp;<\/p>\n<p>After the application of Polydeoxyribonucleotide, care must be taken to obtain a positive result and minimize side effects.<\/p>\n<p>&nbsp;<\/p>\n<ol>\n<li><strong>Hygiene: <\/strong>Keep skin clean, especially in the first few days after treatment.<\/li>\n<li><strong>Hydration: <\/strong>Drink plenty of water to moisturize your skin.<\/li>\n<li><strong>Avoid sun exposure: <\/strong>Protect skin from direct sunlight. It is essential to use a <strong>sunscreen<\/strong> to prevent <strong>hyperpigmentation<\/strong>. <\/li>\n<li><strong>Avoid physical exertion: <\/strong>Avoid intense physical exercise, especially in the first 48 hours after treatment.<\/li>\n<li><strong>Medical follow-up: <\/strong>Maintain regular medical follow-up to monitor results.<\/li>\n<\/ol>\n<p><strong> <\/strong><\/p>\n<p>Do you want to <strong>reduce skin inflammation<\/strong>, <strong>stimulate collagen production<\/strong> or <strong>reduce the appearance of scars and blemishes<\/strong>? PDRN could be the treatment for you. To find out more, <g id=\"gid_3\">book an assessment appointment<\/g> at a Skin Boutique clinic in Porto, Lisbon or Cascais. Our team of doctors will put together a <strong>treatment plan<\/strong> that takes into account your individual characteristics, goals and expectations, so that you can achieve <strong>more beautiful, healthier skin<\/strong>.   <\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: center;\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/skinboutique.pt\/en\/book-an-appointment\/\" target=\"_blank\" rel=\"noopener\">MAKE AN APPOINTMENT<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>PDRN is a substance derived from salmon DNA and acts to regenerate and anti-age the skin. Find out more about this new treatment. <\/p>\n","protected":false},"author":1,"featured_media":11267,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[205],"tags":[314],"class_list":["post-11264","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-treatments","tag-pdrn-en"],"acf":[],"_links":{"self":[{"href":"https:\/\/skinboutique.pt\/en\/wp-json\/wp\/v2\/posts\/11264","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/skinboutique.pt\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/skinboutique.pt\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/skinboutique.pt\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/skinboutique.pt\/en\/wp-json\/wp\/v2\/comments?post=11264"}],"version-history":[{"count":5,"href":"https:\/\/skinboutique.pt\/en\/wp-json\/wp\/v2\/posts\/11264\/revisions"}],"predecessor-version":[{"id":13988,"href":"https:\/\/skinboutique.pt\/en\/wp-json\/wp\/v2\/posts\/11264\/revisions\/13988"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/skinboutique.pt\/en\/wp-json\/wp\/v2\/media\/11267"}],"wp:attachment":[{"href":"https:\/\/skinboutique.pt\/en\/wp-json\/wp\/v2\/media?parent=11264"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/skinboutique.pt\/en\/wp-json\/wp\/v2\/categories?post=11264"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/skinboutique.pt\/en\/wp-json\/wp\/v2\/tags?post=11264"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}